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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRAP2
All Species:
15.15
Human Site:
Y222
Identified Species:
27.78
UniProt:
O75791
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75791
NP_004801.1
330
37909
Y222
Q
Q
P
P
Q
Q
R
Y
L
Q
H
H
H
F
H
Chimpanzee
Pan troglodytes
XP_001166435
403
45969
Y295
Q
Q
P
P
Q
Q
R
Y
L
Q
H
H
H
F
H
Rhesus Macaque
Macaca mulatta
XP_001100458
330
37908
Y222
Q
Q
P
P
Q
Q
R
Y
L
Q
H
H
H
F
H
Dog
Lupus familis
XP_849706
316
36170
Y208
P
P
A
Q
Q
H
R
Y
L
Q
H
P
H
F
H
Cat
Felis silvestris
Mouse
Mus musculus
O89100
322
36792
Q216
G
P
Q
P
P
Q
Q
Q
R
Y
L
Q
H
F
H
Rat
Rattus norvegicus
P62994
217
25188
D113
Q
H
F
K
V
L
R
D
G
A
G
K
Y
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507566
326
37170
Y218
A
Q
Q
P
Q
Q
R
Y
Q
P
Y
H
P
F
Q
Chicken
Gallus gallus
Q07883
217
25058
D113
Q
Q
F
K
V
L
R
D
G
A
G
K
Y
L
L
Frog
Xenopus laevis
P87379
229
26364
F125
Y
F
L
W
V
V
K
F
N
S
L
N
E
L
V
Zebra Danio
Brachydanio rerio
NP_001017756
284
31858
S180
Y
G
S
P
Q
T
S
S
Q
N
R
S
T
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08012
211
24417
F107
C
P
D
G
V
Q
H
F
K
V
L
R
D
A
Q
Honey Bee
Apis mellifera
XP_623354
211
24679
F107
C
S
D
G
V
Q
H
F
K
V
L
R
D
A
Q
Nematode Worm
Caenorhab. elegans
P29355
228
26192
V124
G
K
Y
Y
L
W
A
V
K
F
N
S
L
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.6
98.7
90
N.A.
86
34.8
N.A.
76
33.9
36.9
46.6
N.A.
32.7
33.6
30.6
N.A.
Protein Similarity:
100
81.8
99
91.2
N.A.
90
49.3
N.A.
82.4
48.4
51.5
60.9
N.A.
46
47.2
43.3
N.A.
P-Site Identity:
100
100
100
60
N.A.
33.3
20
N.A.
53.3
20
0
13.3
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
100
60
N.A.
40
26.6
N.A.
60
26.6
20
13.3
N.A.
13.3
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
0
16
0
0
0
16
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
16
0
0
0
0
16
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
8
16
0
0
0
0
24
0
8
0
0
0
54
0
% F
% Gly:
16
8
0
16
0
0
0
0
16
0
16
0
0
0
0
% G
% His:
0
8
0
0
0
8
16
0
0
0
31
31
39
0
39
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
16
0
0
8
0
24
0
0
16
0
0
0
% K
% Leu:
0
0
8
0
8
16
0
0
31
0
31
0
8
16
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
8
8
0
8
0
% N
% Pro:
8
24
24
47
8
0
0
0
0
8
0
8
8
0
0
% P
% Gln:
39
39
16
8
47
54
8
8
16
31
0
8
0
0
24
% Q
% Arg:
0
0
0
0
0
0
54
0
8
0
8
16
0
0
0
% R
% Ser:
0
8
8
0
0
0
8
8
0
8
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
39
8
0
8
0
16
0
0
0
0
8
% V
% Trp:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
8
8
0
0
0
39
0
8
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _